NDLI: Signal processing for a vestibular neurostimulator

Content Provider	IEEE Xplore Digital Library
Author	Rubinstein, J.T. Nie, K. Bierer, S. Ling, L. Phillips, J.O.
Copyright Year	2010
Description	Author affiliation: National Primate Research Center, Virginia Merrill Bloedel Hearing Research Center and Department of Otolaryngology, University of Washington, Seattle, 98195 USA (Phillips, J.O.) \|\| Virginia Merrill Bloedel Hearing Research Center, Departments of Otolaryngology and Bioengineering, University of Washington, Seattle, 98195 USA (Rubinstein, J.T.) \|\| Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, 98195 USA (Nie, K.) \|\| National Primate Research Center, University of Washington, Seattle, 98195 USA (Bierer, S.; Ling, L.)
Abstract	An implanted vestibular neurostimulator has been developed based on commercial cochlear implant technology. It has been implanted chronically in Rhesus monkeys and the physiology of electrical stimulation of the vestibular periphery has been studied. We are currently proposing a human feasibility study of implantation of the device for the treatment of incapacitating Meniere's disease. Because no animal model of Meniere's disease exists, signal processing for such a device must be based on prior observations of human subjects who have suffered Meniere's attacks while their eye-movements could be quantified. Based on such data, and on the leading theories for the pathophysiology of a Meniere's attack, our animal data suggests that fixed amplitude, constant frequency biphasic pulse trains should be adequate to suppress the symptoms of an attack when they occur. The intensity of the stimuli and efficacy of vertigo suppression should be readily modulated either by amplitude or frequency adjustments.
Starting Page	6247
Ending Page	6247
File Size	265541
Page Count	1
File Format	PDF
ISBN	9781424441235
ISSN	1557170X
DOI	10.1109/IEMBS.2010.5628064
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-08-31
Publisher Place	Argentina
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Auditory system USA Councils Surgery Diseases Frequency modulation Humans
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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