NDLI: A modular 256-channel Micro Electrode Array platform for in vitro and in vivo neural stimulation and recording: BioMEA™

Content Provider	IEEE Xplore Digital Library
Author	Charvet, G. Billoint, O. Gharbi, S. Heuschkel, M. Georges, C. Kauffmann, T. Pellissier, A. Yvert, B. Guillemaud, R.
Copyright Year	2010
Description	Author affiliation: CEA/LETI/MINATEC Department DACLE, Grenoble, France (Billoint, O.) \|\| CNRS, UMR5228, Bordeaux, France (Yvert, B.) \|\| Bio-Logic SAS, Claix, France (Georges, C.; Kauffmann, T.; Pellissier, A.) \|\| CEA/LETI/CLINATEC, Grenoble, France (Charvet, G.) \|\| CEA/LETI/MINATEC Department DTBS, Grenoble, France (Gharbi, S.; Guillemaud, R.) \|\| Ayanda Biosystems SA, Lausanne, Switzerland (Heuschkel, M.)
Abstract	In order to understand the dynamics of large neural networks, where information is widely distributed over thousands of cells, one of today's challenges is to successfully monitor the simultaneous activity of as many neurons as possible. This is made possible by using the Micro-Electrode Array (MEA) technology allowing neural cell culture and/or tissue slice experimentation in vitro. Thanks to development of microelectronics' technologies, a novel data acquisition system based on MEA technology has been developed, the BioMEA™. It combines the most advanced MEA biochips with integrated electronics, and a novel user-friendly software interface. To move from prototype (result of the RMNT research project NEUROCOM) to manufactured product, a number of changes have been made. Here, we present a 256-channel MEA data acquisition system with integrated electronics (BioMEA™) allowing simultaneous recording and stimulation of neural networks for in vitro and in vivo applications. This integration is a first step towards an implantable device for BCI (Brain Computer Interface) studies and neural prosthesis.
Starting Page	1804
Ending Page	1807
File Size	1209232
Page Count	4
File Format	PDF
ISBN	9781424441235
ISSN	1557170X
DOI	10.1109/IEMBS.2010.5626403
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-08-31
Publisher Place	Argentina
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	In vivo In vitro Neurons Application specific integrated circuits Arrays Microelectrodes
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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