NDLI: Modeling and simulation of platelet reaction and diffusion towards an electro-stimulating dental implant

Content Provider	IEEE Xplore Digital Library
Author	Delenda, B. Bader, R. van Rienen, U.
Copyright Year	2015
Description	Author affiliation: Fac. of Comput. Sci. & Electr. Eng., Univ. of Rostock, Rostock, Germany (Delenda, B.; van Rienen, U.) \|\| Dept. of Orthopaedics, Univ. Med. of Rostock, Rostock, Germany (Bader, R.)
Abstract	Electrical stimulation (ES) has been used clinically to promote bone ingrowth on implant surface. The osseointegration of biomaterials in bone requires complex biological interactions between different bone cells species. At the early stages of bone healing, it is reported in literature that platelets play an important role in stimulating stem cells, osteogenic cells and osteoblasts. This work studies the coupling of the reaction-diffusion model of platelets with external ES. For this, we introduce a mathematical model framework consisting of a system of coupled partial differential equations. Platelets' migration and interaction within a realistic 3D model adapted from an electro-stimulating dental implant is studied. DC voltage of 3.1 V is applied at the electrodes. The electric field distribution around the electro-stimulating dental implant is simulated. High concentration of platelets around the implant surface is achieved after one day of healing. Based on these results, it is shown that osseointegration of dental implants in bone could be enhanced and accelerated by means of ES.
Starting Page	2584
Ending Page	2587
File Size	912830
Page Count	4
File Format	PDF
ISSN	1557170X
e-ISBN	9781424492718
DOI	10.1109/EMBC.2015.7318920
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2015-08-25
Publisher Place	Italy
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Implants Bones Electric fields Mathematical model Dentistry Cancellous bone Cathodes
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

The impact of bone microstructure on the field distribution of electrostimulative implants

Development of a dental implant mobility measurement system using an inductive sensor

Phase velocity and attenuation predictions of waves in cancellous bone using an iterative effective medium approximation

Optimization of coil geometries for bone fracture healing via dielectrophoretic force stimulation - a simulation study

Local analysis of trabecular bone fracture

Identification of widely applicable configurations for the electrostimulative total hip revision system

Ultrasound imaging of dental implants

Gene Expression of Four Adhesive Proteins in the Early Healing of Bone Defect and Bone-implant Interface

Navigation for cochlear implantation

Modeling and simulation of platelet reaction and diffusion towards an electro-stimulating dental implant

Similar Documents

The impact of bone microstructure on the field distribution of electrostimulative implants

Development of a dental implant mobility measurement system using an inductive sensor

Phase velocity and attenuation predictions of waves in cancellous bone using an iterative effective medium approximation

Optimization of coil geometries for bone fracture healing via dielectrophoretic force stimulation - a simulation study

Local analysis of trabecular bone fracture

Identification of widely applicable configurations for the electrostimulative total hip revision system

Ultrasound imaging of dental implants

Gene Expression of Four Adhesive Proteins in the Early Healing of Bone Defect and Bone-implant Interface

Navigation for cochlear implantation

Modeling and simulation of platelet reaction and diffusion towards an electro-stimulating dental implant