NDLI: A head-mountable microscope for high-speed fluorescence brain imaging

Content Provider	IEEE Xplore Digital Library
Author	Osman, A. Park, J.H. Dickensheets, D. Platisa, J. Culurciello, E. Pieribone, V.A.
Copyright Year	2011
Description	Author affiliation: Electrical Engineering Department, Yale University, USA (Park, J.H.; Culurciello, E.) \|\| Montana State University, Bozeman, USA (Dickensheets, D.) \|\| The John B. Pierce Laboratory, New Haven, CT, USA (Osman, A.; Platisa, J.; Pieribone, V.A.)
Abstract	In this paper we present a rodent head-mountable, fully self contained imaging device that is capable of recording high speed fluorescent signals from genetically-encoded probes or voltage sensitive dyes. This device enables the study of neuronal activity in awake and mobile animals during more natural behaviors without the stress and suppression of anesthesia and restraints. The device is a fully self contained fluorescence microscope, illumination system and image sensor. The total weight of the system is 10 g and is capable of imaging up to 890 fps. We are currently running voltage dye experiments using the system on the somatosensory cortex of a mouse during whisker stimulation.
Starting Page	114
Ending Page	116
File Size	1446399
Page Count	3
File Format	PDF
ISBN	9781457714696
e-ISBN	9781457714702
DOI	10.1109/BioCAS.2011.6107740
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2011-11-10
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Optical fibers Microscopy Fluorescence Light emitting diodes Optical imaging Optical sensors
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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