NDLI: Electrocatalytic boost up of epinephrine and its simultaneous resolution in the presence of serotonin and folic acid at poly(serine)/multi-walled carbon nanotubes composite modified electrode: A voltammetric study.

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Electrocatalytic boost up of epinephrine and its simultaneous resolution in the presence of serotonin and folic acid at poly(serine)/multi-walled carbon nanotubes composite modified electrode: A voltammetric study.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Narayana, P. V. Madhusudana Reddy, T. Gopal, P. Mohan Reddy, M. Ramakrishna Naidu, G.
Description	Country affiliation: India Author Affiliation: Narayana PV ( Electrochemical Research Laboratory, Department of Chemistry, SVU College of Sciences, Sri Venkateswara University, Tirupati 517 502, Andhra Pradesh, India.); Madhusudana Reddy T ( Electrochemical Research Laboratory, Department of Chemistry, SVU College of Sciences, Sri Venkateswara University, Tirupati 517 502, Andhra Pradesh, India. Electronic address: tmsreddysvu@gmail.com.); Gopal P ( Electrochemical Research Laboratory, Department of Chemistry, SVU College of Sciences, Sri Venkateswara University, Tirupati 517 502, Andhra Pradesh, India.); Mohan Reddy M ( Department of Psychiatry, Sri Devaraj Ur's Acedamy of Higher Education and Research (SDUAHER), Tamaka, Kolar, Karnataka, India.); Ramakrishna Naidu G ( Department of Environmental Sciences, SVU College of Sciences, Sri Venkateswara University, Tirupati 517 502, Andhra Pradesh, India.)
Abstract	The present paper describes the new strategy for the development of nanosensor based on dropcasting of multi-walled carbon nanotubes (MWCNTs) followed by electropolymerization of serine (ser) onto the glassy carbon electrode (GCE). The developed nanocomposite sensor was abbreviated as poly(ser)/MWCNTs/GCE and was characterized by using electrochemical impedance spectroscopy (EIS) technique. The EIS results confirmed the fast electron transfer rate at the surface of poly(ser)/MWCNTs/GCE. The proposed sensor exhibited good catalytic activity towards the sensing of epinephrine (EP) individually and simultaneously in the presence of serotonin (5-HT) and folic acid (FA) in 0.1M phosphate buffer solution (PBS) at pH7.0. The limit of detection (LOD) and limit of quantification (LOQ) of EP was found to be 6×10(-7)M and 2×10(-6)M respectively. The fabricated sensor showed excellent precision and accuracy with a relative standard deviation (RSD) of 4.86%. The proposed composite sensor was effectively applied towards the determination of EP in human blood serum and pharmaceutical injection sample.
File Format	HTM / HTML
ISSN	09284931
Volume Number	56
e-ISSN	18730191
Journal	Materials Science and Engineering: C
Language	English
Publisher	Elsevier
Publisher Date	2015-11-01
Publisher Place	Netherlands
Access Restriction	Subscribed
Subject Keyword	Discipline Materials Science Epinephrine Chemistry Folic Acid Nanocomposites Nanotubes, Carbon Serine Serotonin Biosensing Techniques Methods Catalysis Dielectric Spectroscopy Electrochemical Techniques Electrodes Glass Hydrogen-ion Concentration Limit Of Detection Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject Domain (in MeSH)	Inorganic Chemicals Organic Chemicals Heterocyclic Compounds Amino Acids, Peptides, and Proteins Investigative Techniques Equipment and Supplies Chemical Phenomena Technology, Industry, and Agriculture
Subject	Biomaterials Mechanical Engineering Condensed Matter Physics Mechanics of Materials Bioengineering

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