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Content Provider | World Health Organization (WHO)-Global Index Medicus |
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Author | Wang, Sean Xiang Byrnes, Abigail Verma, Sadhna Pancoast, John R. Rixe, Olivier |
Description | Country affiliation: United States Author Affiliation: Wang SX ( Division of Hematology/Oncology, University of Cincinnati College of Medicine, Cincinnati, OH, USA. wang2x2@ucmail.uc.edu) |
Abstract | Hepatocellular carcinoma (HCC) is a highly aggressive cancer. For patients who are diagnosed with advanced stage disease that are not surgical candidates, the disease is universally lethal. Advance has been made to extend survival with molecular target therapy, but durable complete responses are extremely rare. We report an unusual case where a 74-year-old patient with unresectable HCC received eight months of reduced-dose of sorafenib, a tyrosine kinase inhibitor, and achieved a durable complete remission. At the most recent follow up, he remains in remission 16 months after cessation of treatment, without clinical or imaging evidence of disease recurrence. |
File Format | HTM / HTML |
ISSN | 17762596 |
Issue Number | 1 |
Volume Number | 5 |
e-ISSN | 1776260X |
Journal | Targeted Oncology |
Language | English |
Publisher | Springer |
Publisher Date | 2010-03-01 |
Publisher Place | France |
Access Restriction | Subscribed |
Subject Keyword | Discipline Oncology Benzenesulfonates Administration & Dosage Carcinoma, Hepatocellular Drug Therapy Hepacivirus Pathogenicity Hepatitis C, Chronic Liver Neoplasms Protein Kinase Inhibitors Pyridines Aged Etiology Pathology Physiopathology Drug Dosage Calculations Complications Humans Liver Cirrhosis Male Niacinamide Analogs & Derivatives Phenylurea Compounds Remission Induction Case Reports Journal Article |
Content Type | Text |
Resource Type | Case study Article |
Subject Domain (in MeSH) | Eukaryota Viruses Virus Diseases Neoplasms Digestive System Diseases Organic Chemicals Heterocyclic Compounds Chemical Actions and Uses Therapeutics Persons |
Subject | Oncology Cancer Research Pharmacology (medical) |
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