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Content Provider | IEEE Xplore Digital Library |
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Author | Wear, K.A. |
Copyright Year | 2007 |
Description | Author affiliation: Food & Drug Adm., Silver Spring (Wear, K.A.) |
Abstract | Clinical SOS measurements exhibit a high degree of inter-system variability. Calcaneal SOS is usually computed from time-of-flight measurements of broadband ultrasound pulses that propagate through the foot. In order to minimize the effects of multi-path interference, many investigators measure time-of-flight from markers near the leading edge of the pulse. The calcaneus is a highly attenuating, highly inhomogeneous bone that distorts propagating ultrasound pulses via frequency- dependent attenuation, reverberation, dispersion, multiple scattering, and refraction. This pulse distortion can produce errors in leading-edge transit-time marker based SOS measurements. In this paper, an equation to predict dependence of time-domain SOS measurements on system parameters (center frequency and bandwidth), transit-time marker location, and bone properties (attenuation coefficient and thickness) is validated with through-transmission measurements in a bone- mimicking phantom and in 73 women in vivo, using a clinical bone sonometer. In order to test the utility of the formula for suppressing system dependence of SOS measurements, a wideband laboratory data acquisition system was used to make a second set of through-transmission measurements on the phantom. The compensation formula reduced system-dependent leading-edge transit-time marker based SOS measurements in the phantom from 41 m/s to 5 m/s and reduced transit-time marker related SOS variability in 73 women from 40 m/s to 10 m/s. The compensation formula can be used to improve standardization in bone sonometry. |
Starting Page | 2159 |
Ending Page | 2162 |
File Size | 194526 |
Page Count | 4 |
File Format | |
ISBN | 9781424413836 |
ISSN | 10510117 |
DOI | 10.1109/ULTSYM.2007.543 |
Language | English |
Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
Publisher Date | 2007-10-28 |
Publisher Place | USA |
Access Restriction | Subscribed |
Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
Subject Keyword | Standardization In vivo Time domain analysis Velocity measurement Ultrasonic variables measurement Pulse measurements Distortion measurement Bones Imaging phantoms Ultrasonic imaging |
Content Type | Text |
Resource Type | Article |
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