NDLI: Experimental evaluation of a deformable registration algorithm for motion correction in PET-CT guided biopsy

Content Provider	IEEE Xplore Digital Library
Author	Khare, R. Sala, G. Kinahan, P. Esposito, G. Banovac, F. Cleary, K. Enquobahrie, A.
Copyright Year	2013
Description	Author affiliation: Kitware Inc., Carrboro, NC, USA (Sala, G.; Enquobahrie, A.) \|\| Univ. of Washington, Seattle, WA, USA (Kinahan, P.) \|\| Children's Nat. Med. Center, Washington, DC, USA (Khare, R.; Cleary, K.) \|\| Georgetown Univ. Hosp., Washington, DC, USA (Esposito, G.; Banovac, F.)
Abstract	Positron emission tomography computed tomography (PET-CT) images are increasingly being used for guidance during percutaneous biopsy. However, due to the physics of image acquisition, PET-CT images are susceptible to problems due to respiratory and cardiac motion, leading to inaccurate tumor localization, shape distortion, and attenuation correction. To address these problems, we present a method for motion correction that relies on respiratory gated CT images aligned using a deformable registration algorithm. In this work, we use two deformable registration algorithms and two optimization approaches for registering the CT images obtained over the respiratory cycle. The two algorithms are the BSpline and the symmetric forces Demons registration. In the first optmization approach, CT images at each time point are registered to a single reference time point. In the second approach, deformation maps are obtained to align each CT time point with its adjacent time point. These deformations are then composed to find the deformation with respect to a reference time point. We evaluate these two algorithms and optimization approaches using respiratory gated CT images obtained from 7 patients. Our results show that overall the BSpline registration algorithm with the reference optimization approach gives the best results.
Starting Page	1
Ending Page	5
File Size	163857
Page Count	5
File Format	PDF
e-ISBN	9781479905348
DOI	10.1109/NSSMIC.2013.6829037
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-10-27
Publisher Place	South Korea
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Computed tomography Positron emission tomography Biopsy Optimization Splines (mathematics) Lungs motion correction PET-CT deformable registration image-guided surgery
Content Type	Text
Resource Type	Article

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