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Content Provider | IEEE Xplore Digital Library |
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Author | Bolea, J. Pueyo, E. Laguna, P. Bailon, R. |
Copyright Year | 2014 |
Description | Author affiliation: Aragon Inst. for Eng. Res., Univ. of Zaragoza, Zaragoza, Spain (Bolea, J.; Pueyo, E.; Laguna, P.; Bailon, R.) |
Abstract | Heart rate variability (HRV) has been studied as a non-invasive technique to characterize the autonomic nervous system (ANS) regulation of the heart. Non-linear methods based on chaos theory have been used during the last decades as markers for risk stratification. However, interpretation of these nonlinear methods in terms of sympathetic and parasympathetic activity is not fully established. In this work we study linear and non-linear HRV indices during ANS blockades in order to assess their relation with sympathetic and parasympathetic activities. Power spectral content in low frequency (0.04-0.15Hz) and high frequency (0.15-0.4Hz) bands of HRV, as well as correlation dimension, sample and approximate entropies were computed in a database of subjects during single and dual ANS blockade with atropine and/or propranolol. Parasympathetic blockade caused a significant decrease in the low and high frequency power of HRV, as well as in correlation dimension and sample and approximate entropies. Sympathetic blockade caused a significant increase in approximate entropy. Sympathetic activation due to postural change from supine to standing caused a significant decrease in all the investigated non-linear indices and a significant increase in the normalized power in the low frequency band. The other investigated linear indices did not show significant changes. Results suggest that parasympathetic activity has a direct relation with sample and approximate entropies. |
Sponsorship | IEEE Eng. Med. Biol. Soc. |
Starting Page | 3252 |
Ending Page | 3255 |
File Size | 740957 |
Page Count | 4 |
File Format | |
ISBN | 9781424479290 |
ISSN | 1557170X |
DOI | 10.1109/EMBC.2014.6944316 |
Language | English |
Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
Publisher Date | 2014-08-26 |
Publisher Place | USA |
Access Restriction | Subscribed |
Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
Subject Keyword | Heart rate variability Correlation Electrocardiography Entropy Resonant frequency Time series analysis |
Content Type | Text |
Resource Type | Article |
Subject | Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition |
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