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Content Provider | IEEE Xplore Digital Library |
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Author | Tanifuji, T. Ohtomo, T. Ishikawa, T. Ichitsubo, K. |
Copyright Year | 2004 |
Description | Author affiliation: Dept. of Electr. & Electron. Eng., Kitami Inst. of Technol., Japan (Tanifuji, T.; Ohtomo, T.; Ishikawa, T.; Ichitsubo, K.) |
Abstract | Time-resolved reflectance of an optical pulse from a four-layered adult head model including cerebrospinal fluid (CSF) has been analyzed based on the finite difference time domain analysis (FDTD) which has been formulated by authors. It has been confirmed that the intensity of the reflected light and the mean time of flight dependences on the source-detector separations estimated from the time-resolved reflectance agree quite well with the previously reported experiments and calculations. The sensitivities for detecting optical property changes of gray and white matter beyond CSF in time-resolved reflectance have been evaluated and it has been become clear that they are enhanced compared with the sensitivities in the intensity of the reflected light and the mean time of flight. The derivatives of reflectance with respect to the absorption coefficients of gray and white matter have shown that the presence of CSF improves the capabilities of time-resolved reflectance for detecting optical property changes in the brain in actual noise limited photon detection systems. |
Starting Page | 1248 |
Ending Page | 1251 |
File Size | 423732 |
Page Count | 4 |
File Format | |
ISBN | 0780384393 |
DOI | 10.1109/IEMBS.2004.1403396 |
Language | English |
Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
Publisher Date | 2004-09-01 |
Publisher Place | USA |
Access Restriction | Subscribed |
Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
Subject Keyword | Finite difference methods Time domain analysis Reflectivity Optical pulses Optical scattering Biomedical optical imaging Head Optical sensors Optical noise Light scattering time-resolved reflectance FDTD analysis imaging of brain activity optical tomography |
Content Type | Text |
Resource Type | Article |
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