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Content Provider | IEEE Xplore Digital Library |
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Author | Zirnheld, J.L. Zucker, S.N. DiSanto, T.M. Berezney, R. Etemadi, K. |
Copyright Year | 1973 |
Abstract | A nonthermal plasma torch has been developed to study the targeted killing of melanoma cells. In this paper, 1205Lu melanoma cells and keratinocytes were exposed to the plasma. These cells were transfected with green fluorescent protein in order to establish a system for coculture with primary keratinocytes. Results show that a 10 s treatment with plasma causes a morphological change in the melanoma cells, as observed after 18 h. However, after only 15 min following plasma treatment, a significant killing of melanoma cells was observed, with a much reduced killing of keratinocytes. Nonthermal plasma may serve as an effective tool for future therapeutic cancer treatment. |
Sponsorship | IEEE Nuclear and Plasma Sciences Society |
Starting Page | 948 |
Ending Page | 952 |
Page Count | 5 |
File Size | 467193 |
File Format | |
ISSN | 00933813 |
Volume Number | 38 |
Issue Number | 4 |
Language | English |
Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
Publisher Date | 2010-04-01 |
Publisher Place | U.S.A. |
Access Restriction | One Nation One Subscription (ONOS) |
Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
Subject Keyword | Needles Malignant tumors Plasma devices Plasma sources Plasma properties Plasma applications Plasma density Plasma temperature Cancer Plasma materials processing nonequilibrium plasma Atmospheric-pressure plasma jet melanoma cells |
Content Type | Text |
Resource Type | Article |
Subject | Nuclear and High Energy Physics Condensed Matter Physics |
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